Ozbek, Irene N.
Warren, Amye R.; Whitson, Stefanie R.
College of Arts and Sciences
University of Tennessee at Chattanooga
Place of Publication
Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients.
M. S.; A thesis submitted to the faculty of the University of Tennessee at Chattanooga in partial fulfillment of the requirements of the degree of Master of Science.
Smell -- Threshold; Odors -- Psychological aspects
xi, 53 leaves
McKinney, Jessica Mi, "Odor sensitivity and the presence of p-cresol" (2013). Masters Theses and Doctoral Dissertations.