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Modern Psychological Studies

Periodical Title

Modern Psychological Studies

Volume

16

Number

2

Page Numbers

pages 97-107

Department

Dept. of Psychology

Publisher

University of Tennessee at Chattanooga

Place of Publication

Chattanooga (Tenn.)

Date

2011

Abstract

Experience shapes neural circuits in the brain. This review explores current research in neuroscience on experience-dependent synapse formation in mice. Studies using the chessboard trimming paradigm are analyzed to provide information on the effects of partial versus complete deprivation. The resulting formation of transient spines and new persistent spines indicates the impact experience has on shaping neural pathways. Research on long-term sensory deprivation in the adolescent and adult somatosensory cortex indicates that once brain pathways are established in adulthood, they are difficult to change. Together these findings are applied to the questions presented in the literature of developmental psychopathology, such as the implications of spine growth and elimination in Attention Deficit Hyperactive Disorder and Antisocial Personality Disorder. Future research is limited by the ethical concerns of imaging dendritic spines in humans; however, the findings outlined in this review hold speculative results for experience-dependent synapse formation in humans.

Subject

Psychology

Discipline

Psychology

Document Type

articles

Extent

11 leaves

Language

English

Call Number

BF1 .M63 v. 16 no. 2 2011

Rights

http://rightsstatements.org/vocab/InC/1.0/

Included in

Psychology Commons

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