University of Tennessee at Chattanooga
Place of Publication
Major depressive disorder is commonly known for its prevalence and impairing effects on the brain and behavior. One such effect is a decrease in processing speed, which leads to slower response times and an increased difficulty performing tasks that require careful attention. Impairments in spatial ability have also been reported in depressed subjects, which may be linked to impairments in executive functioning. GABA is a neurotransmitter that has been shown to play a role in the symptoms of depression. This review will examine the effects of depression on cognitive functioning and the brain, and will suggest that future research examine the link between low concentrations of GABA in the brain and performance on cognitive tasks in depressed patients.
Stewart, Ashlee and Harburger, Lauren L.
"The effects of major depressive disorder on cognition and the brain,"
Modern Psychological Studies: Vol. 26
, Article 5.
Available at: https://scholar.utc.edu/mps/vol26/iss1/5