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Modern Psychological Studies

Periodical Title

Modern Psychological Studies

Volume

3

Number

2

Page Numbers

pages 29-35

Department

Dept. of Psychology

Publisher

University of Tennessee at Chattanooga

Place of Publication

Chattanooga (Tenn.)

Date

1995

Abstract

Glucagon is a pancreatic hormone and a brain-gut peptide thought to function as a short-term satiety signal in control of food intake. This study examined effects of glucagon injection on intake of alcohol, food, and water. Overnight water-deprived female and male Wistar rats (Ns = 10) were given access to 5% w/v ethanol and Purina chow. After adaptation to this schedule, rats received intraperitoneal (ip) injection of 0, 200, or 400 g/kg of glucagon, at 0 or 30 min prior to alcohol access. Food intake was significantly increased by glucagon at 30-60 min after either time of injection (0 or 30 min). Combined total caloric intake (from chow and ethanol) was decreased at 0-30 min after glucagon injection, and increased at 30-60 min after glucagon, reliably in male rats. Immediate declines and delayed increases in feeding after glucagon administration have been reported previously in other feeding paradigms. In addition to acting as a short-term satiety signal for caloric intake, glucagon may function further to sustain blood glucose levels through stimulation of delayed increase in food intake.

Subject

Psychology

Discipline

Psychology

Document Type

articles

Extent

7 leaves

Language

English

Call Number

BF1 .M63 v. 3 no. 2 1995

Rights

http://rightsstatements.org/vocab/InC/1.0/

Included in

Psychology Commons

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