Project Director
Lynch, John
Department Examiner
Mebane, Robert; Whitson, Kristin
Publisher
University of Tennessee at Chattanooga
Place of Publication
Chattanooga (Tenn.)
Abstract
Electronic cigarettes, or e-cigarettes, have been scrutinized by the Food and Drug Administration and other public health organizations for issues related to quality control and efficacy. Erratic nicotine delivery and numerous toxic compounds in refill solutions have been reported. The ultimate goal of this research is to add to the growing amount of knowledge regarding e-cigarette ingredient content, safety, and quality. Standards of the tobacco alkaloids nicotine, anabasine, cotinine, and myosmine were prepared and quantified using high performance liquid chromatography (HPLC). Various elution schemes were tested and adjusted for optimal analyte resolution, and a final elution scheme was developed to characterize e-cigarette alkaloids.
Degree
B. S.; An honors thesis submitted to the faculty of the University of Tennessee at Chattanooga in partial fulfillment of the requirements of the degree of Bachelor of Science.
Date
5-2014
Subject
Electronic cigarettes
Discipline
Chemicals and Drugs | Chemistry
Document Type
Theses
Extent
64 leaves
DCMI Type
Text
Language
English
Rights
http://rightsstatements.org/vocab/InC/1.0/
License
http://creativecommons.org/licenses/by-sa/3.0/
Recommended Citation
Murray, Jessica L., "Nicotine and what else?: HPLC elution optimization for the analysis of alkaloids found in electronic cigarettes" (2014). Honors Theses.
https://scholar.utc.edu/honors-theses/3
Department
Dept. of Chemistry