Committee Chair

Gao, Cuilan

Committee Member

Wang, Jin; Gunasekera, Sumith; Nichols, Roger

Department

Dept. of Mathematics

College

College of Arts and Sciences

Publisher

University of Tennessee at Chattanooga

Place of Publication

Chattanooga (Tenn.)

Abstract

Hyperchloremia (high serum chloride level) is frequently observed in critically ill patients in the intensive care unit (ICU). Clinical evidence shows that hyperchloremia is associated with increased in-hospital mortality. Length of hospital stay (LOS) is often used as an indicator of hospital efficiency, a proxy of resource consumption and is especially important in organizing hospital services. Such data often have a highly right-skewed distribution for non-zero values and possible excess zero counts. Our study aims to examine the association of serum chloride levels at different time points with hospital mortality and to model the length of hospital and ICU stays in conjunction with zero-inflated and overdispersed count data. This research will consider the use of several univariate and multivariate models to evaluate the effects of serum chloride as it pertains to patient mortality. This research resulted from application to more than 1700 critically ill patients from a local hospital.

Degree

M. S.; A thesis submitted to the faculty of the University of Tennessee at Chattanooga in partial fulfillment of the requirements of the degree of Master of Science.

Date

8-2019

Subject

Inflation (Finance) -- Mathematical models; Medical statistics

Keyword

Zero-inflation; Overdispersion; In-hospital mortality

Document Type

Masters theses

Extent

xi, 28 leaves

Language

English

Rights

Under copyright.

License

http://creativecommons.org/licenses/by/4.0/

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